Cell Signaling Technology releases VISTA rabbit monoclonal antibody

his announcement was made at the CRI-CIMT-EATI-AACR Inaugural International Cancer Immunotherapy Conference: Translating Science into Survival, September 16-19, 2015 in New York, NY.

VISTA (V-Domain Ig Suppressor of T Cell Activation, C10orf54, GI24, SISP1) is a negative checkpoint control protein that regulates T cell activation and immune response. Its role in negative checkpoint control has made it an important target in the field of tumor immunology; a field that seeks to develop better therapeutic options by dismantling the mechanisms tumors use to generate and thrive in their own immunosuppressive microenvironments.

VISTA (D1L2G) XP Rabbit mAb #64953 is validated, using CST’s rigorous standards, to recognize human VISTA in immunohistochemistry and western blot research applications.

Today’s announcement follows the release of a suite of antibodies designed to recognize pivotal targets within the field of tumor immunology research. These include PD-L1 (E1L3N) XP Rabbit mAb #13684, PD-1 (D3W4U) Rabbit mAb #15121, CTLA-4 (D4E9I) Rabbit mAb #15119, OX40 (D1S6L) Rabbit mAb #15123, B7-H3 (D9M2L) XP Rabbit mAb #14058, and B7-H4 (D1M8I) XP Rabbit mAb #14572.

CST CEO Michael Comb said: ""We feel the release of these products strengthens our position as a leading supplier of complete turnkey solutions to the tumor immunology community. We recognize that the study of tumor immunology has the potential to improve both our understanding of how cancer progresses and our approach to treating it, as such we are pleased to offer products that help advance this important field of study.