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Sorrento completes patient enrollment in Cynviloq TRIBECA registrational trial By PBR Staff Writer
US-based Sorrento Therapeutics has completed patient enrollment in its ongoing TRIBECA (TRIal establishing bioequivalence [BE] between Cynviloq and Albumin-bound paclitaxel) registrational trial.
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Adamis receives notice of allowance for US and Japanese patents for dry powder inhaler Taper DPI Adamis Pharmaceuticals recently received a notice of allowance that one of its patent applications for its proprietary dry powder inhaler, Taper DPI, will issue in the United States (U.S. Patent Application No. 13/320,762) and in Japan (Japanese Patent Application No. 2012-511965).
Automation > IT & Software > News Goodwin, Transporin enter technology collaboration to improve ability of antibody drug conjugates Goodwin Biotechnology, a biological Contract Manufacturing Organization (CMO) that specializes in Mammalian Cell Culture expression systems and Bioconjugation technologies, and Transporin, a Silicon Valley R & D company with full ownership of IP rights to a broad array of life science and software technologies, have announced a collaboration whereby Goodwin Biotechnology has been granted a worldwide, exclusive license to utilize the proprietary metal-binding domain (MBD) of human insulin-like growth factor binding protein-3 (IGFBP-3) conjugated to monoclonal antibodies or antibody fusion proteins, and perform process development and manufacturing services using such conjugates for research, evaluation, and clinical trial purposes.
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Envisia begins Phase IIa trial of ENV515 to treat glaucoma patients
By PBR Staff Writer
US-based biotechnology firm Envisia Therapeutics has started a Phase IIa clinical trial designed to evaluate the safety and tolerability of its lead product, ENV515, in patients with glaucoma.
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Enlivex secures EU orphan drug status for ApoCell to treat GvHD
By PBR Staff Writer
Israel-based Enlivex Therapeutics has received orphan drug status from the European Medicines Agency (EMA) for its lead product candidate, ApoCell, to prevent graft-versus-host disease (GvHD).
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Syncona, UCLB form cancer immunotherapy firm Autolus
Syncona and UCL Business, the wholly-owned technology transfer company of University College London, announce the creation of Autolus Limited, a biopharmaceutical company focused on the development and commercialisation of next-generation engineered T-cell therapies for haematological and solid tumours.
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Trovagene expands clinical collaboration with Genomac
Trovagene, announced it will expand the clinical collaboration with Genomac Research Institute in Prague, Czech Republic.
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Critical Outcome Technologies planning phase I trial of COTI-2 in recurrent head and neck cancers
Critical Outcome Technologies, the biopharmaceutical company that uses machine learning to rapidly develop targeted therapies, announced today that it has executed a material transfer agreement ("MTA") with Dr. John Yoo, MD, FRCSC, FACS, and his team at the London Health Sciences Centre's London Regional Cancer Program and Western University, for the continued evaluation of COTI-2 for the treatment of patients with recurrent head and neck squamous cell cancer ("HNSCC").
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Spark begins Phase I/II trial of SPK-CHM to treat Choroideremia
By PBR Staff Writer
US-based gene therapy company Spark Therapeutics has started enrollment in a Phase I/II clinical trial of its product candidate, SPK-CHM, to treat patients with choroideremia (CHM), an X-linked inherited retinal dystrophy.
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Oncore agrees to merge with Tekmira to develop NVP018 for hepatitis B treatment
US biotechnology company OnCore Biopharma (OnCore), which has licensed NeuroVive’s drug candidate NVP018 for the treatment of chronic Hepatitis B virus infection (HBV), has agreed to merge with Canadian listed RNAi therapeutics company Tekmira Pharmaceuticals (Tekmira).
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Evotec enters into research collaboration with C4X Discovery
By PBR Staff Writer
German drug discovery firm Evotec and UK-based C4X Discovery Holdings (C4XD) have entered into a research collaboration to optimize Orexin-1 selective inhibitors discovered through C4XD's NMR technology.
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Oramed granted patent in Israel for Oral Administration of GLP-1
Oramed Pharmaceuticals, a clinical-stage pharmaceutical company focused on the development of oral drug delivery systems, announced that the Israel Patent Office has granted the Company's patent for its invention, titled "Methods and Compositions for Oral Administrations of Exenatide."
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